Chlorine in PDB 6t4w: Ror(Gamma)T Ligand Binding Domain in Complex with 20-Alpha- Hydroxycholesterol and Allosteric Ligand Glenmark

The structure of Ror(Gamma)T Ligand Binding Domain in Complex with 20-Alpha- Hydroxycholesterol and Allosteric Ligand Glenmark, PDB code: 6t4w was solved by R.M.J.M.De Vries, F.A.Meijer, L.Brunsveld, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	54.16 / 1.71
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	108.317, 108.317, 99.332, 90.00, 90.00, 120.00
R / Rfree (%)	16 / 20

The binding sites of Chlorine atom in the Ror(Gamma)T Ligand Binding Domain in Complex with 20-Alpha- Hydroxycholesterol and Allosteric Ligand Glenmark (pdb code 6t4w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Ror(Gamma)T Ligand Binding Domain in Complex with 20-Alpha- Hydroxycholesterol and Allosteric Ligand Glenmark, PDB code: 6t4w:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Ror(Gamma)T Ligand Binding Domain in Complex with 20-Alpha- Hydroxycholesterol and Allosteric Ligand Glenmark


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Ror(Gamma)T Ligand Binding Domain in Complex with 20-Alpha- Hydroxycholesterol and Allosteric Ligand Glenmark within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl803 b:26.8 occ:1.00 CL1 A:MJE803 0.0 26.8 1.0 C16 A:MJE803 1.8 23.7 1.0 C15 A:MJE803 2.7 22.5 1.0 C17 A:MJE803 2.8 25.0 1.0 C14 A:MJE803 3.0 23.1 1.0 N2 A:MJE803 3.4 22.6 1.0 N1 A:MJE803 3.4 21.3 1.0 C A:LEU324 3.5 21.1 1.0 N A:THR325 3.5 22.5 0.5 N A:THR325 3.5 22.0 0.6 CG2 A:THR325 3.6 22.5 0.6 CB A:LEU324 3.6 20.8 1.0 O A:LEU324 3.6 21.9 1.0 O3 A:MJE803 3.7 25.6 1.0 CE A:MET358 3.7 28.9 1.0 CA A:THR325 3.8 22.5 0.6 CA A:THR325 3.9 24.4 0.5 C20 A:MJE803 4.0 24.7 1.0 C18 A:MJE803 4.0 25.2 1.0 OG1 A:THR325 4.1 27.9 0.5 CA A:LEU324 4.1 21.0 1.0 CG1 A:ILE328 4.2 23.1 1.0 CD1 A:LEU483 4.2 25.5 1.0 CB A:THR325 4.3 21.9 0.6 C4 A:MJE803 4.4 22.6 1.0 O A:ALA321 4.4 22.7 1.0 C6 A:MJE803 4.4 22.4 1.0 C19 A:MJE803 4.5 25.1 1.0 CB A:THR325 4.6 25.3 0.5 CG A:LEU324 4.9 22.4 1.0 CB A:ILE328 4.9 23.2 1.0 C5 A:MJE803 5.0 23.3 1.0 C13 A:MJE803 5.0 23.9 1.0

Chlorine binding site 2 out of 2 in the Ror(Gamma)T Ligand Binding Domain in Complex with 20-Alpha- Hydroxycholesterol and Allosteric Ligand Glenmark


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Ror(Gamma)T Ligand Binding Domain in Complex with 20-Alpha- Hydroxycholesterol and Allosteric Ligand Glenmark within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl803 b:29.6 occ:1.00 CL2 A:MJE803 0.0 29.6 1.0 C20 A:MJE803 1.8 24.7 1.0 C19 A:MJE803 2.7 25.1 1.0 C15 A:MJE803 2.7 22.5 1.0 C14 A:MJE803 3.0 23.1 1.0 O3 A:MJE803 3.2 25.6 1.0 CD A:GLN484 3.4 31.1 1.0 OE1 A:GLN484 3.5 32.6 1.0 NE2 A:GLN484 3.6 30.7 1.0 O A:HOH912 3.7 30.6 1.0 N2 A:MJE803 3.8 22.6 1.0 C18 A:MJE803 4.0 25.2 1.0 C16 A:MJE803 4.0 23.7 1.0 CG A:GLN484 4.0 31.9 1.0 O A:LEU505 4.1 25.6 1.0 CZ A:PHE506 4.2 24.7 1.0 CD1 A:LEU505 4.3 23.9 1.0 N1 A:MJE803 4.3 21.3 1.0 CE2 A:PHE506 4.3 26.8 1.0 CB A:LEU483 4.4 24.3 1.0 C17 A:MJE803 4.5 25.0 1.0 N A:GLN484 4.5 25.5 1.0 CB A:LEU505 4.6 22.8 1.0 CE1 A:PHE506 4.6 26.4 1.0 C A:LEU483 4.6 25.4 1.0 CA A:GLN484 4.6 26.8 1.0 C4 A:MJE803 4.7 22.6 1.0 O A:LEU483 4.8 26.1 1.0 C A:LEU505 4.9 24.7 1.0 CG1 A:VAL480 4.9 27.1 1.0 CB A:GLN484 4.9 27.9 1.0 CG A:LEU505 4.9 23.2 1.0 CD2 A:PHE506 4.9 26.0 1.0 O A:VAL480 5.0 28.4 1.0

R.M.J.M.De Vries, F.A.Meijer, R.G.Doveston, L.Brunsveld. Ror(Gamma)T Ligand Binding Domain in Complex with 20-Alpha-Hydroxycholesterol and Allosteric Ligand Glenmark To Be Published.