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Chlorine in PDB 6xsy: The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site

Enzymatic activity of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site

All present enzymatic activity of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site:
4.2.1.20;

Protein crystallography data

The structure of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site, PDB code: 6xsy was solved by E.Hilario, L.J.Mueller, M.F.Dunn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.91 / 1.55
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 181.42, 58.69, 67.28, 90, 94.42, 90
R / Rfree (%) 13.8 / 17.9

Other elements in 6xsy:

The structure of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site also contains other interesting chemical elements:

Caesium (Cs) 4 atoms
Fluorine (F) 3 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site (pdb code 6xsy). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 9 binding sites of Chlorine where determined in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site, PDB code: 6xsy:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9;

Chlorine binding site 1 out of 9 in 6xsy

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Chlorine binding site 1 out of 9 in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl312

b:40.0
occ:1.00
 O A:HOH681 2.8 41.7 1.0
O A:HOH569 3.3 15.0 1.0
O A:HOH489 3.8 16.6 1.0
O A:HOH556 3.8 21.5 1.0
CD1 A:PHE114 3.9 9.4 1.0
O A:HOH533 4.0 19.1 1.0
O A:HOH553 4.1 26.8 1.0
O B:HOH542 4.1 15.9 1.0
CE2 A:PHE82 4.3 19.2 1.0
CE1 A:PHE114 4.3 9.9 1.0
O B:HOH840 4.4 23.8 1.0
O A:HOH628 4.6 27.2 1.0
CD2 A:PHE82 4.7 17.0 1.0
O A:LEU105 4.7 10.2 1.0
CG A:PHE114 5.0 9.4 1.0
CA A:PHE114 5.0 9.4 1.0

Chlorine binding site 2 out of 9 in 6xsy

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Chlorine binding site 2 out of 9 in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl313

b:84.6
occ:1.00
 O A:HOH677 3.0 33.0 1.0
O A:HOH479 3.3 19.4 1.0
O A:HOH417 3.5 26.0 1.0
O A:HOH702 3.7 19.6 1.0
CD A:GLU218 4.0 23.4 1.0
OE1 A:GLU218 4.1 26.4 1.0
CG A:GLU218 4.2 18.8 1.0
O A:HOH777 4.2 44.3 1.0
CB A:GLU218 4.3 15.4 1.0
O A:HOH679 4.4 17.6 1.0
OE2 A:GLU218 4.4 31.4 1.0
NH2 A:ARG225 4.5 17.3 1.0
O A:GLU218 4.5 12.5 1.0
O A:HOH621 4.7 40.9 1.0
CB A:ALA222 4.9 12.6 1.0
C A:GLU218 4.9 12.2 1.0

Chlorine binding site 3 out of 9 in 6xsy

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Chlorine binding site 3 out of 9 in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl314

b:22.8
occ:1.00
 O B:HOH794 2.4 5.3 0.6
O A:HOH636 2.8 63.4 1.0
O A:PHE107 3.0 12.3 1.0
O B:HOH824 3.3 31.9 1.0
O B:HOH794 3.5 9.0 0.4
O A:ASN108 3.6 15.5 1.0
CE2 A:PHE107 3.7 14.5 1.0
CZ A:PHE107 3.9 14.0 1.0
CD2 A:PHE107 4.0 12.8 1.0
N A:GLY110 4.0 13.0 1.0
C A:ASN108 4.1 14.2 1.0
C A:PHE107 4.1 11.2 1.0
CE1 A:PHE107 4.3 14.3 1.0
CG A:PHE107 4.4 11.4 1.0
CA A:GLY110 4.5 12.2 1.0
CD1 A:PHE107 4.5 13.3 1.0
O B:HOH1003 4.6 30.1 1.0
O A:HOH587 4.7 16.9 1.0
N A:ASN109 4.7 14.1 1.0
CA A:ASN108 4.7 12.1 1.0
C A:ASN109 4.8 14.3 1.0
N A:ASN108 4.9 11.8 1.0
CA A:ASN109 4.9 14.8 1.0

Chlorine binding site 4 out of 9 in 6xsy

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Chlorine binding site 4 out of 9 in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl315

b:10.4
occ:1.00
 O A:HOH659 2.3 30.1 1.0
O A:HOH431 2.3 32.9 1.0
O A:ARG267 3.1 29.4 1.0
OG A:SER221 3.1 10.7 0.4
O A:ALA265 3.2 14.8 1.0
O A:HOH554 3.4 51.1 1.0
OG A:SER221 3.7 12.3 0.2
O A:HOH637 3.8 43.1 1.0
CB A:SER221 3.9 9.7 0.3
CB A:SER221 4.0 11.8 0.2
CB A:SER221 4.0 10.4 0.4
C A:ALA265 4.1 13.2 1.0
C A:ARG267 4.2 29.4 1.0
CA A:SER221 4.5 10.1 0.3
CA A:SER221 4.5 11.3 0.2
CA A:SER221 4.5 10.6 0.4
N A:ARG267 4.6 19.6 1.0
C A:SER266 4.6 14.6 1.0
O A:SER266 4.9 17.9 1.0
CA A:ALA265 4.9 12.4 1.0
N A:SER266 4.9 12.4 1.0
O A:HOH461 5.0 35.1 1.0

Chlorine binding site 5 out of 9 in 6xsy

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Chlorine binding site 5 out of 9 in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl418

b:15.3
occ:1.00
 O B:SER249 3.0 15.4 1.0
O B:ASP225 3.1 11.9 1.0
O B:HOH618 3.3 23.5 1.0
N B:GLY251 4.0 9.5 1.0
C B:ASP225 4.0 9.7 1.0
C B:SER249 4.2 14.1 1.0
O B:HOH922 4.3 49.8 1.0
O B:HOH947 4.3 24.3 1.0
CA B:ASP225 4.4 10.3 1.0
O B:HOH678 4.5 33.6 1.0
CB B:ASP225 4.5 10.5 1.0
O B:HOH940 4.5 31.3 0.4
CA B:GLY251 4.6 9.3 1.0
O B:HOH950 4.7 24.1 1.0
C B:VAL250 4.8 9.6 1.0
CA B:VAL250 4.9 10.6 1.0
OD1 B:ASP225 4.9 14.6 1.0
N B:VAL250 4.9 12.7 1.0

Chlorine binding site 6 out of 9 in 6xsy

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Chlorine binding site 6 out of 9 in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl419

b:39.4
occ:1.00
 O B:HOH822 2.8 53.3 1.0
O B:HOH584 2.9 36.5 1.0
N B:GLU369 3.0 11.4 0.8
N B:GLU369 3.0 10.0 0.2
CB B:GLU369 3.5 15.0 0.8
CB B:GLU369 3.6 10.4 0.2
CA B:GLU369 3.8 12.2 0.8
CA B:GLU369 3.8 9.7 0.2
C B:LYS368 3.9 9.6 1.0
CA B:LYS368 3.9 10.0 1.0
O B:GLU367 4.1 12.1 1.0
O B:GLU369 4.3 12.3 0.8
O B:GLU369 4.3 9.8 0.2
C B:GLU369 4.5 11.3 0.8
CG B:LYS368 4.5 10.4 1.0
C B:GLU369 4.6 9.8 0.2
NH2 B:ARG70 4.8 35.9 1.0
CB B:LYS368 4.8 9.6 1.0
O B:HOH621 4.9 35.8 1.0
CG B:GLU369 4.9 21.5 0.8
N B:LYS368 4.9 9.2 1.0
C B:GLU367 5.0 10.5 1.0
OE1 B:GLU369 5.0 12.4 0.2
CZ B:ARG70 5.0 29.7 1.0

Chlorine binding site 7 out of 9 in 6xsy

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Chlorine binding site 7 out of 9 in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl420

b:37.4
occ:1.00
 OD2 B:ASP323 3.0 16.2 1.0
O B:HOH613 3.2 22.6 1.0
O B:HOH759 3.6 42.4 1.0
CG B:ASP323 3.9 12.2 1.0
O B:HOH667 4.1 13.9 1.0
O B:HOH755 4.1 27.8 1.0
OD1 B:ASP323 4.1 12.9 1.0
O B:HOH947 4.7 24.3 1.0
O B:HOH914 4.9 51.3 1.0
O B:GLY320 5.0 11.8 1.0

Chlorine binding site 8 out of 9 in 6xsy

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Chlorine binding site 8 out of 9 in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl421

b:51.7
occ:1.00
 O B:HOH598 3.0 55.8 1.0
C B:LEU5 3.4 17.4 1.0
O B:LEU4 3.5 20.6 1.0
N B:ASN6 3.5 17.4 1.0
O B:LEU5 3.7 17.0 1.0
C B:LEU4 3.8 17.0 1.0
O B:THR3 3.8 19.3 1.0
CA B:LEU5 3.8 17.1 1.0
N B:LEU5 3.9 16.2 1.0
CA B:ASN6 4.1 15.3 1.0
OG1 B:THR3 4.3 19.1 1.0
C B:THR3 4.5 15.5 1.0
CB B:ASN6 4.8 17.9 1.0
CA B:LEU4 4.8 15.1 1.0
O B:HOH793 4.8 37.2 1.0
N B:LEU4 5.0 15.9 1.0

Chlorine binding site 9 out of 9 in 6xsy

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Chlorine binding site 9 out of 9 in the The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4- (Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy)Methyl]Pyridin-4- Yl}Methylidene)-L-Serine (Kou) at the Beta-Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl422

b:63.7
occ:1.00
 CG B:TYR8 3.6 10.5 1.0
CD1 B:TYR8 3.7 11.4 1.0
CD2 B:TYR8 3.7 11.7 1.0
CE1 B:TYR8 3.8 12.5 1.0
CE2 B:TYR8 3.9 13.0 1.0
CZ B:TYR8 3.9 13.0 1.0
OE2 B:GLU11 4.0 35.4 1.0
O B:HOH595 4.1 20.0 1.0
O B:GLY10 4.1 13.8 1.0
CB B:TYR8 4.3 10.0 1.0
O B:HOH671 4.3 29.8 1.0
O B:HOH696 4.4 57.0 1.0
CD B:GLU11 4.5 30.6 1.0
OE1 B:GLU11 4.5 37.4 1.0
OH B:TYR8 4.7 15.1 1.0
CA B:GLU11 4.9 13.0 1.0

Reference:

E.Hilario, M.F.Dunn, L.J.Mueller. The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant Beta-S377A with Inhibitor 2-({[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Amino) Ethyl Dihydrogen Phosphate (F9F) at the Alpha-Site, Cesium Ion at the Metal Coordination Site, and (E)-N-({3-Hydroxy-2-Methyl-5-[(Phosphonooxy) Methyl]Pyridin-4-Yl}Methylidene)-L-Serine (Kou) at the Beta-Site. To Be Published.
Page generated: Mon Jul 29 17:21:44 2024

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