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Chlorine in PDB 7fgy: Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase (Tgdhfr-Ts) Complexed with P40, Nadph and DumpEnzymatic activity of Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase (Tgdhfr-Ts) Complexed with P40, Nadph and Dump
All present enzymatic activity of Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase (Tgdhfr-Ts) Complexed with P40, Nadph and Dump:
1.5.1.3; 2.1.1.45; Protein crystallography data
The structure of Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase (Tgdhfr-Ts) Complexed with P40, Nadph and Dump, PDB code: 7fgy
was solved by
J.Vanichtanankul,
A.Yoomuang,
S.Taweechai,
T.Saeyang,
J.Yuvaniyama,
B.Tarnchompoo,
Y.Yuthavong,
S.Kamchonwongpaisan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase (Tgdhfr-Ts) Complexed with P40, Nadph and Dump
(pdb code 7fgy). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase (Tgdhfr-Ts) Complexed with P40, Nadph and Dump, PDB code: 7fgy: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 7fgyGo back to Chlorine Binding Sites List in 7fgy
Chlorine binding site 1 out
of 4 in the Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase (Tgdhfr-Ts) Complexed with P40, Nadph and Dump
Mono view Stereo pair view
Chlorine binding site 2 out of 4 in 7fgyGo back to Chlorine Binding Sites List in 7fgy
Chlorine binding site 2 out
of 4 in the Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase (Tgdhfr-Ts) Complexed with P40, Nadph and Dump
Mono view Stereo pair view
Chlorine binding site 3 out of 4 in 7fgyGo back to Chlorine Binding Sites List in 7fgy
Chlorine binding site 3 out
of 4 in the Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase (Tgdhfr-Ts) Complexed with P40, Nadph and Dump
Mono view Stereo pair view
Chlorine binding site 4 out of 4 in 7fgyGo back to Chlorine Binding Sites List in 7fgy
Chlorine binding site 4 out
of 4 in the Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase (Tgdhfr-Ts) Complexed with P40, Nadph and Dump
Mono view Stereo pair view
Reference:
J.Vanichtanankul,
A.Yoomuang,
S.Taweechai,
T.Saeyang,
J.Pengon,
J.Yuvaniyama,
B.Tarnchompoo,
Y.Yuthavong,
S.Kamchonwongpaisan.
Structural Insight Into Effective Inhibitors' Binding to Toxoplasma Gondii Dihydrofolate Reductase Thymidylate Synthase. Acs Chem.Biol. V. 17 1691 2022.
Page generated: Tue Apr 4 20:37:16 2023
ISSN: ESSN 1554-8937 PubMed: 35715223 DOI: 10.1021/ACSCHEMBIO.1C00627 |
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