Atomistry » Chlorine » PDB 2oa1-2ol1 » 2oc2
Atomistry »
  Chlorine »
    PDB 2oa1-2ol1 »
      2oc2 »

Chlorine in PDB 2oc2: Structure of Testis Ace with RXPA380

Enzymatic activity of Structure of Testis Ace with RXPA380

All present enzymatic activity of Structure of Testis Ace with RXPA380:
3.4.15.1;

Protein crystallography data

The structure of Structure of Testis Ace with RXPA380, PDB code: 2oc2 was solved by H.R.Corradi, C.S.Anthony, S.L.Schwager, P.Redelinghuys, D.Georgiadis, V.Dive, K.R.Acharya, E.D.Sturrock, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 17.12 / 2.25
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 56.514, 84.763, 133.483, 90.00, 90.00, 90.00
R / Rfree (%) 21.5 / 26.2

Other elements in 2oc2:

The structure of Structure of Testis Ace with RXPA380 also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of Testis Ace with RXPA380 (pdb code 2oc2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Testis Ace with RXPA380, PDB code: 2oc2:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 2oc2

Go back to Chlorine Binding Sites List in 2oc2
Chlorine binding site 1 out of 2 in the Structure of Testis Ace with RXPA380


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Testis Ace with RXPA380 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl703

b:16.6
occ:1.00
O A:HOH743 3.1 8.3 1.0
NH1 A:ARG489 3.2 13.7 1.0
NE1 A:TRP485 3.2 10.1 1.0
NE A:ARG186 3.3 18.4 1.0
CZ2 A:TRP486 3.4 12.6 1.0
NH1 A:ARG186 3.5 17.3 1.0
NE A:ARG489 3.6 13.9 1.0
CZ A:ARG489 3.6 13.2 1.0
CB A:ASP507 3.8 15.2 1.0
CZ A:ARG186 3.9 17.8 1.0
CH2 A:TRP486 3.9 12.5 1.0
CE2 A:TRP485 4.0 10.6 1.0
CE2 A:TRP486 4.1 12.2 1.0
CD1 A:TRP485 4.2 9.2 1.0
CZ2 A:TRP485 4.2 10.7 1.0
CZ2 A:TRP182 4.4 16.6 1.0
O A:ASP507 4.4 14.6 1.0
CD A:ARG186 4.4 18.8 1.0
NE1 A:TRP486 4.5 12.8 1.0
CG A:ASP507 4.5 15.4 1.0
O A:HOH724 4.6 3.0 1.0
OD2 A:ASP507 4.7 16.3 1.0
CD A:ARG489 4.7 14.2 1.0
NH2 A:ARG489 4.7 13.3 1.0
C A:ASP507 4.8 14.8 1.0
CA A:ASP507 4.8 15.4 1.0
NE1 A:TRP182 5.0 16.9 1.0
CZ3 A:TRP486 5.0 13.0 1.0
CE2 A:TRP182 5.0 17.5 1.0

Chlorine binding site 2 out of 2 in 2oc2

Go back to Chlorine Binding Sites List in 2oc2
Chlorine binding site 2 out of 2 in the Structure of Testis Ace with RXPA380


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Testis Ace with RXPA380 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl704

b:20.2
occ:1.00
O A:HOH763 2.9 26.1 1.0
OH A:TYR224 2.9 18.9 1.0
CE1 A:TYR224 3.4 17.9 1.0
CZ A:TYR224 3.6 18.6 1.0
CB A:ARG522 3.6 13.2 1.0
NE A:ARG522 3.6 12.9 1.0
CB A:PRO519 3.6 14.0 1.0
N A:ARG522 3.7 13.6 1.0
CB A:PRO407 3.7 12.7 1.0
CE A:MET223 3.8 23.8 1.0
CG A:PRO407 3.8 13.1 1.0
CG2 A:ILE521 3.9 13.9 1.0
CA A:ARG522 4.0 13.2 1.0
NH2 A:ARG522 4.0 13.2 1.0
CG A:ARG522 4.2 13.2 1.0
CZ A:ARG522 4.3 13.5 1.0
CG A:PRO519 4.4 14.2 1.0
SD A:MET223 4.5 23.9 1.0
CD A:ARG522 4.5 12.9 1.0
O A:HOH706 4.5 9.9 1.0
C A:ILE521 4.6 13.6 1.0
CD1 A:TYR224 4.7 17.4 1.0
C A:PRO519 4.7 14.1 1.0
N A:ILE521 4.8 13.3 1.0
CA A:PRO519 4.8 14.1 1.0
CD A:PRO407 4.8 13.4 1.0
O A:PRO519 4.9 14.2 1.0
O A:TRP220 4.9 16.0 1.0
CE2 A:TYR224 4.9 18.2 1.0
CA A:ILE521 5.0 13.7 1.0

Reference:

C.S.Anthony, H.R.Corradi, S.L.Schwager, P.Redelinghuys, D.Georgiadis, V.Dive, K.R.Acharya, E.D.Sturrock. The N Domain of Human Angiotensin-I Converting Enzyme: the Role of N-Glycosylation and the Crystal Structure in Complex with An N Domain Specific Phosphinic Inhibitor RXP407. J.Biol.Chem. V. 46 5473 2010.
ISSN: ISSN 0021-9258
PubMed: 20826823
DOI: 10.1074/JBC.M110.167866
Page generated: Sat Jul 20 09:29:05 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy