|
Atomistry » Chlorine » PDB 2oa1-2ol1 » 2oji | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2oa1-2ol1 » 2oji » |
Chlorine in PDB 2oji: Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-CarboxamideEnzymatic activity of Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide
All present enzymatic activity of Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide:
2.7.11.24; Protein crystallography data
The structure of Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide, PDB code: 2oji
was solved by
X.Xie,
M.D.Jacobs,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide
(pdb code 2oji). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide, PDB code: 2oji: Chlorine binding site 1 out of 1 in 2ojiGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide
![]() Mono view ![]() Stereo pair view
Reference:
A.M.Aronov,
C.Baker,
G.W.Bemis,
J.Cao,
G.Chen,
P.J.Ford,
U.A.Germann,
J.Green,
M.R.Hale,
M.Jacobs,
J.W.Janetka,
F.Maltais,
G.Martinez-Botella,
M.N.Namchuk,
J.Straub,
Q.Tang,
X.Xie.
Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole Erk Inhibitors. J.Med.Chem. V. 50 1280 2007.
Page generated: Sat Jul 20 09:33:44 2024
ISSN: ISSN 0022-2623 PubMed: 17300186 DOI: 10.1021/JM061381F |
Last articlesZn in 9MJ5Zn in 9HNW Zn in 9G0L Zn in 9FNE Zn in 9DZN Zn in 9E0I Zn in 9D32 Zn in 9DAK Zn in 8ZXC Zn in 8ZUF |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |