Chlorine in PDB 7ljd: Allosteric Modulator LY3154207 Binding to Dopamine-Bound Dopamine Receptor 1 in Complex with Minigs Protein

The binding sites of Chlorine atom in the Allosteric Modulator LY3154207 Binding to Dopamine-Bound Dopamine Receptor 1 in Complex with Minigs Protein (pdb code 7ljd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Allosteric Modulator LY3154207 Binding to Dopamine-Bound Dopamine Receptor 1 in Complex with Minigs Protein, PDB code: 7ljd:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Allosteric Modulator LY3154207 Binding to Dopamine-Bound Dopamine Receptor 1 in Complex with Minigs Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Allosteric Modulator LY3154207 Binding to Dopamine-Bound Dopamine Receptor 1 in Complex with Minigs Protein within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl502 b:47.4 occ:1.00 CL9 R:G4C502 0.0 47.4 1.0 C08 R:G4C502 1.8 47.4 1.0 C10 R:G4C502 2.7 47.4 1.0 C07 R:G4C502 2.7 47.4 1.0 C06 R:G4C502 3.0 47.4 1.0 O15 R:G4C502 3.6 47.4 1.0 C05 R:G4C502 3.8 47.4 1.0 NE1 R:TRP123 3.9 33.6 1.0 C11 R:G4C502 4.0 47.4 1.0 C13 R:G4C502 4.0 47.4 1.0 NH1 R:ARG130 4.2 48.0 1.0 CE2 R:TRP123 4.2 33.6 1.0 CZ R:ARG130 4.3 48.0 1.0 CZ2 R:TRP123 4.3 33.6 1.0 NH2 R:ARG130 4.4 48.0 1.0 C12 R:G4C502 4.5 47.4 1.0 CD1 R:TRP123 4.6 33.6 1.0 NE R:ARG130 4.9 48.0 1.0 CD2 R:TRP123 5.0 33.6 1.0

Chlorine binding site 2 out of 2 in the Allosteric Modulator LY3154207 Binding to Dopamine-Bound Dopamine Receptor 1 in Complex with Minigs Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Allosteric Modulator LY3154207 Binding to Dopamine-Bound Dopamine Receptor 1 in Complex with Minigs Protein within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl502 b:47.4 occ:1.00 CL4 R:G4C502 0.0 47.4 1.0 C13 R:G4C502 1.8 47.4 1.0 C12 R:G4C502 2.7 47.4 1.0 C07 R:G4C502 2.7 47.4 1.0 C06 R:G4C502 3.1 47.4 1.0 C05 R:G4C502 3.5 47.4 1.0 C17 R:G4C502 3.7 47.4 1.0 CE3 R:TRP123 3.9 33.6 1.0 CB R:LYS134 3.9 51.5 1.0 O15 R:G4C502 4.0 47.4 1.0 C11 R:G4C502 4.0 47.4 1.0 N04 R:G4C502 4.0 47.4 1.0 C08 R:G4C502 4.0 47.4 1.0 CD2 R:TRP123 4.1 33.6 1.0 CA R:TYR131 4.1 43.3 1.0 CB R:TRP123 4.2 33.6 1.0 C16 R:G4C502 4.2 47.4 1.0 O R:ARG130 4.2 48.0 1.0 CG R:TRP123 4.2 33.6 1.0 CD1 R:TYR131 4.4 43.3 1.0 N R:TYR131 4.5 43.3 1.0 C10 R:G4C502 4.5 47.4 1.0 C R:ARG130 4.6 48.0 1.0 CE R:MET135 4.6 53.9 1.0 CZ3 R:TRP123 4.6 33.6 1.0 N R:MET135 4.6 53.9 1.0 CG R:LYS134 4.7 51.5 1.0 CB R:TYR131 4.8 43.3 1.0 CG R:ARG130 4.8 48.0 1.0 CB R:MET135 4.8 53.9 1.0 CE2 R:TRP123 5.0 33.6 1.0 C R:LYS134 5.0 51.5 1.0 CA R:LYS134 5.0 51.5 1.0

Y.Zhuang, B.Krumm, H.Zhang, X.E.Zhou, Y.Wang, J.Guo, X.-P.Huang, Y.Liu, L.Wang, X.Cheng, Y.Jiang, H.Jiang, K.Melcher, C.Zhang, W.Yi, B.L.Roth, Y.Zhang, H.E.Xu. Mechanism of Dopamine Binding and Allosteric Modulation of the Human D1 Dopamine Receptor Biorxiv 2021.
DOI: 10.1101/2021.02.07.430101