Chlorine in PDB 1su3: X-Ray Structure of Human Prommp-1: New Insights Into Collagenase Action

All present enzymatic activity of X-Ray Structure of Human Prommp-1: New Insights Into Collagenase Action:
3.4.24.7;

The structure of X-Ray Structure of Human Prommp-1: New Insights Into Collagenase Action, PDB code: 1su3 was solved by D.Jozic, G.Bourenkov, N.H.Lim, H.Nagase, W.Bode, K.Maskos, Structural Proteomics In Europe (Spine), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.20
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	142.746, 142.746, 295.308, 90.00, 90.00, 90.00
R / Rfree (%)	22.3 / 25.2

The structure of X-Ray Structure of Human Prommp-1: New Insights Into Collagenase Action also contains other interesting chemical elements:

Zinc	(Zn)	4 atoms
Calcium	(Ca)	8 atoms
Sodium	(Na)	2 atoms

The binding sites of Chlorine atom in the X-Ray Structure of Human Prommp-1: New Insights Into Collagenase Action (pdb code 1su3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the X-Ray Structure of Human Prommp-1: New Insights Into Collagenase Action, PDB code: 1su3:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the X-Ray Structure of Human Prommp-1: New Insights Into Collagenase Action


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure of Human Prommp-1: New Insights Into Collagenase Action within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl909 b:35.1 occ:1.00 NA A:NA911 2.8 44.0 1.0 O A:ILE287 3.5 41.9 1.0 N A:ILE287 3.5 38.3 1.0 N A:ALA380 3.5 39.7 1.0 N A:VAL429 3.6 40.0 1.0 N A:ALA331 3.6 39.9 1.0 O A:ALA331 3.7 40.0 1.0 CA A:ALA428 3.7 40.3 1.0 CA A:ALA379 3.7 38.8 1.0 O A:VAL429 3.8 40.8 1.0 CB A:ALA379 3.8 38.9 1.0 O A:ALA380 3.8 42.0 1.0 CA A:ALA330 3.8 41.1 1.0 CA A:ALA286 3.9 36.5 1.0 CB A:ALA286 4.0 36.8 1.0 CB A:ALA428 4.1 40.5 1.0 CB A:ALA330 4.1 40.5 1.0 C A:ALA428 4.2 39.9 1.0 C A:ALA379 4.2 39.0 1.0 C A:ALA330 4.2 40.6 1.0 C A:ALA286 4.2 37.0 1.0 C A:ILE287 4.4 40.7 1.0 CA A:ILE287 4.5 39.3 1.0 C A:ALA331 4.5 40.4 1.0 CA A:ALA331 4.6 39.9 1.0 CA A:ALA380 4.6 41.0 1.0 C A:VAL429 4.6 40.7 1.0 CA A:VAL429 4.6 40.0 1.0 C A:ALA380 4.6 42.4 1.0 O A:ASP427 4.7 41.0 1.0 CG1 A:VAL429 4.8 41.1 1.0 O A:ASP378 4.8 40.0 1.0 N A:ALA428 4.9 40.7 1.0 O A:GLU329 4.9 42.8 1.0 N A:ALA379 5.0 38.9 1.0

Chlorine binding site 2 out of 2 in the X-Ray Structure of Human Prommp-1: New Insights Into Collagenase Action


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of X-Ray Structure of Human Prommp-1: New Insights Into Collagenase Action within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl910 b:34.4 occ:1.00 NA B:NA912 2.9 34.8 1.0 N B:ILE287 3.5 34.8 1.0 N B:ALA380 3.5 36.5 1.0 O B:ILE287 3.5 35.0 1.0 N B:VAL429 3.5 37.5 1.0 N B:ALA331 3.6 35.0 1.0 CA B:ALA428 3.7 37.1 1.0 CA B:ALA379 3.7 35.8 1.0 O B:ALA331 3.7 35.7 1.0 O B:ALA380 3.8 37.5 1.0 CB B:ALA379 3.8 35.6 1.0 O B:VAL429 3.8 38.6 1.0 CA B:ALA286 3.8 35.4 1.0 CA B:ALA330 3.9 35.1 1.0 CB B:ALA428 3.9 37.1 1.0 CB B:ALA286 4.0 35.6 1.0 C B:ALA428 4.1 37.3 1.0 C B:ALA379 4.1 36.0 1.0 C B:ALA286 4.1 35.0 1.0 C B:ALA330 4.3 35.0 1.0 CB B:ALA330 4.3 35.6 1.0 C B:ILE287 4.4 35.2 1.0 CA B:ILE287 4.5 34.5 1.0 CA B:ALA380 4.5 37.2 1.0 CG1 B:VAL429 4.6 37.7 1.0 C B:ALA380 4.6 38.2 1.0 C B:ALA331 4.6 35.6 1.0 CA B:ALA331 4.6 35.0 1.0 O B:ASP427 4.6 36.6 1.0 CA B:VAL429 4.6 37.3 1.0 C B:VAL429 4.6 38.3 1.0 O B:GLU329 4.8 36.8 1.0 N B:ALA428 4.9 37.4 1.0 O B:ASP378 4.9 36.7 1.0 N B:ALA379 5.0 36.0 1.0

D.Jozic, G.Bourenkov, N.H.Lim, R.Visse, H.Nagase, W.Bode, K.Maskos. X-Ray Structure of Human Prommp-1: New Insights Into Procollagenase Activation and Collagen Binding. J.Biol.Chem. V. 280 9578 2005.
ISSN: ISSN 0021-9258
PubMed: 15611040
DOI: 10.1074/JBC.M411084200