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Atomistry » Chlorine » PDB 3d4i-3dgo » 3dbe » |
Chlorine in PDB 3dbe: Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 557Enzymatic activity of Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 557
All present enzymatic activity of Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 557:
2.7.11.21; Protein crystallography data
The structure of Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 557, PDB code: 3dbe
was solved by
R.A.Elling,
K.J.Barr,
M.J.Romanowski,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 557
(pdb code 3dbe). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 557, PDB code: 3dbe: Chlorine binding site 1 out of 1 in 3dbeGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 557
![]() Mono view ![]() Stereo pair view
Reference:
R.V.Fucini,
E.J.Hanan,
M.J.Romanowski,
R.A.Elling,
W.Lew,
K.J.Barr,
J.Zhu,
J.C.Yoburn,
Y.Liu,
B.T.Fahr,
J.Fan,
Y.Lu,
P.Pham,
I.C.Choong,
E.C.Vanderporten,
M.Bui,
H.E.Purkey,
M.J.Evanchik,
W.Yang.
Design and Synthesis of 2-Amino-Pyrazolopyridines As Polo-Like Kinase 1 Inhibitors. Bioorg.Med.Chem.Lett. V. 18 5648 2008.
Page generated: Fri Jul 11 04:24:30 2025
ISSN: ISSN 0960-894X PubMed: 18793847 DOI: 10.1016/J.BMCL.2008.08.095 |
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