|
Atomistry » Chlorine » PDB 5h3g-5hi2 » 5hez | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5h3g-5hi2 » 5hez » |
Chlorine in PDB 5hez: JAK2 Kinase (JH1 Domain) Mutant P1057A in Complex with TG101209Enzymatic activity of JAK2 Kinase (JH1 Domain) Mutant P1057A in Complex with TG101209
All present enzymatic activity of JAK2 Kinase (JH1 Domain) Mutant P1057A in Complex with TG101209:
2.7.10.2; Protein crystallography data
The structure of JAK2 Kinase (JH1 Domain) Mutant P1057A in Complex with TG101209, PDB code: 5hez
was solved by
M.Ultsch,
C.Eigenbrot,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5hez:
The structure of JAK2 Kinase (JH1 Domain) Mutant P1057A in Complex with TG101209 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the JAK2 Kinase (JH1 Domain) Mutant P1057A in Complex with TG101209
(pdb code 5hez). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the JAK2 Kinase (JH1 Domain) Mutant P1057A in Complex with TG101209, PDB code: 5hez: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 5hezGo back to Chlorine Binding Sites List in 5hez
Chlorine binding site 1 out
of 3 in the JAK2 Kinase (JH1 Domain) Mutant P1057A in Complex with TG101209
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 5hezGo back to Chlorine Binding Sites List in 5hez
Chlorine binding site 2 out
of 3 in the JAK2 Kinase (JH1 Domain) Mutant P1057A in Complex with TG101209
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 5hezGo back to Chlorine Binding Sites List in 5hez
Chlorine binding site 3 out
of 3 in the JAK2 Kinase (JH1 Domain) Mutant P1057A in Complex with TG101209
Mono view Stereo pair view
Reference:
C.A.Dendrou,
A.Cortes,
L.Shipman,
H.G.Evans,
K.E.Attfield,
L.Jostins,
T.Barber,
G.Kaur,
S.B.Kuttikkatte,
O.A.Leach,
C.Desel,
S.L.Faergeman,
J.Cheeseman,
M.J.Neville,
S.Sawcer,
A.Compston,
A.R.Johnson,
C.Everett,
J.I.Bell,
F.Karpe,
M.Ultsch,
C.Eigenbrot,
G.Mcvean,
L.Fugger.
Resolving TYK2 Locus Genotype-to-Phenotype Differences in Autoimmunity. Sci Transl Med V. 8 RA149 2016.
Page generated: Sat Dec 12 11:48:25 2020
ISSN: ESSN 1946-6242 PubMed: 27807284 DOI: 10.1126/SCITRANSLMED.AAG1974 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |