Chlorine in PDB 5wkx: Barium Sites in the Structure of A Resting Acid Sensing Ion Channel

The structure of Barium Sites in the Structure of A Resting Acid Sensing Ion Channel, PDB code: 5wkx was solved by N.Yoder, E.Gouaux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.66 / 4.03
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	108.010, 126.300, 156.320, 90.00, 90.00, 90.00
R / Rfree (%)	30.2 / 31.3

The structure of Barium Sites in the Structure of A Resting Acid Sensing Ion Channel also contains other interesting chemical elements:

Barium

(Ba)

1 atom

The binding sites of Chlorine atom in the Barium Sites in the Structure of A Resting Acid Sensing Ion Channel (pdb code 5wkx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Barium Sites in the Structure of A Resting Acid Sensing Ion Channel, PDB code: 5wkx:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Barium Sites in the Structure of A Resting Acid Sensing Ion Channel


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Barium Sites in the Structure of A Resting Acid Sensing Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl502 b:0.6 occ:1.00 NZ A:LYS422 2.8 0.3 1.0 CB B:PRO73 3.3 0.2 1.0 CA B:PRO73 3.4 0.8 1.0 NZ A:LYS77 3.5 0.3 1.0 N B:HIS74 4.0 0.2 1.0 CD A:LYS77 4.0 93.4 1.0 CE A:LYS77 4.0 95.6 1.0 CE A:LYS422 4.2 0.7 1.0 C B:PRO73 4.2 0.8 1.0 O B:HIS74 4.3 0.9 1.0 N B:PRO73 4.5 0.5 1.0 CG B:PRO73 4.7 0.4 1.0 CD A:LYS422 5.0 95.7 1.0 O B:TYR72 5.0 0.1 1.0

Chlorine binding site 2 out of 3 in the Barium Sites in the Structure of A Resting Acid Sensing Ion Channel


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Barium Sites in the Structure of A Resting Acid Sensing Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl503 b:0.1 occ:1.00 NZ C:LYS422 3.3 0.1 1.0 NZ C:LYS77 3.9 97.5 1.0 O A:LEU71 4.0 0.3 1.0 CA A:PRO73 4.1 0.6 1.0 CB A:PRO73 4.2 0.2 1.0 CB A:LEU71 4.3 0.9 1.0 N A:PRO73 4.7 0.7 1.0 O A:TYR72 4.7 0.7 1.0 C A:LEU71 4.7 0.3 1.0 CE C:LYS422 4.8 0.9 1.0 C A:TYR72 4.9 0.3 1.0 CD1 A:LEU71 4.9 0.6 1.0

Chlorine binding site 3 out of 3 in the Barium Sites in the Structure of A Resting Acid Sensing Ion Channel


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Barium Sites in the Structure of A Resting Acid Sensing Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl504 b:0.4 occ:1.00 NZ B:LYS422 3.1 0.5 1.0 CB C:PRO73 3.4 0.1 1.0 CA C:PRO73 3.8 0.8 1.0 NZ B:LYS77 4.1 0.9 1.0 CE B:LYS422 4.4 0.3 1.0 CG C:PRO73 4.7 0.2 1.0 N C:PRO73 4.7 0.6 1.0 N C:HIS74 4.8 0.6 1.0 CB C:LEU71 4.9 0.5 1.0 CD1 C:LEU71 4.9 0.1 1.0 CD B:LYS77 4.9 0.6 1.0 C C:PRO73 4.9 0.3 1.0 CE B:LYS77 4.9 1.0 1.0

N.Yoder, E.Gouaux. Divalent Cation and Chloride Ion Sites of Chicken Acid Sensing Ion Channel 1A Elucidated By X-Ray Crystallography. Plos One V. 13 02134 2018.
ISSN: ESSN 1932-6203
PubMed: 30157194
DOI: 10.1371/JOURNAL.PONE.0202134