Chlorine in PDB 5zhc: Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV

The structure of Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV, PDB code: 5zhc was solved by K.Meera, R.K.Pal, A.Arora, B.K.Biswal, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	63.66 / 1.97
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	30.633, 49.099, 127.325, 90.00, 90.00, 90.00
R / Rfree (%)	18.5 / 23.8

The binding sites of Chlorine atom in the Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV (pdb code 5zhc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV, PDB code: 5zhc:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl201 b:58.4 occ:1.00 OH B:TYR71 3.1 30.9 1.0 NE2 B:HIS48 3.6 29.6 1.0 CD B:ARG69 3.9 30.4 1.0 O B:HOH311 3.9 29.9 1.0 CE1 B:TYR71 4.0 27.4 1.0 CZ B:TYR71 4.0 28.1 1.0 CB B:ARG69 4.3 29.2 1.0 CE1 B:HIS48 4.4 30.3 1.0 CD2 B:HIS48 4.5 29.0 1.0 CG B:ARG69 4.5 29.3 1.0 NE B:ARG69 4.7 31.1 1.0 CG B:TYR44 4.8 38.3 1.0 CD2 B:TYR44 4.8 41.3 1.0 CB B:TYR44 5.0 35.2 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl202 b:61.7 occ:1.00 NH2 B:ARG2 3.3 48.8 1.0 O A:HOH202 3.5 38.2 1.0 NH1 B:ARG2 3.6 48.5 1.0 CZ B:ARG2 3.9 47.8 1.0 N B:GLU-1 4.1 36.0 1.0 CB B:GLU-1 4.1 40.2 1.0 CG B:PRO-2 4.3 40.7 1.0 CB B:PRO-2 4.3 39.8 1.0 CA B:GLU-1 4.4 36.7 1.0 C B:PRO-2 4.6 36.1 1.0 OD1 A:ASP53 4.8 33.9 1.0 OD2 A:ASP53 4.8 31.8 1.0

M.Kumari, R.K.Pal, A.K.Mishra, S.Tripathi, B.K.Biswal, K.K.Srivastava, A.Arora. Structural and Functional Characterization of the Transcriptional Regulator RV3488 Ofmycobacterium TUBERCULOSISH37RV. Biochem. J. V. 475 3393 2018.
ISSN: ESSN 1470-8728
PubMed: 30266832
DOI: 10.1042/BCJ20180356