Chlorine in PDB 6kkt: Human KCC1 Structure Determined in Kcl and Lipid Nanodisc

The structure of Human KCC1 Structure Determined in Kcl and Lipid Nanodisc also contains other interesting chemical elements:

Potassium

(K)

2 atoms

The binding sites of Chlorine atom in the Human KCC1 Structure Determined in Kcl and Lipid Nanodisc (pdb code 6kkt). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Human KCC1 Structure Determined in Kcl and Lipid Nanodisc, PDB code: 6kkt:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Human KCC1 Structure Determined in Kcl and Lipid Nanodisc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human KCC1 Structure Determined in Kcl and Lipid Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1105 b:65.6 occ:1.00 OH A:TYR589 2.9 52.8 1.0 N A:GLY433 3.0 63.7 1.0 N A:ILE434 3.3 68.6 1.0 N A:MET435 3.4 74.1 1.0 CA A:GLY433 3.4 63.7 1.0 CG A:MET435 3.5 74.1 1.0 C A:GLY433 3.6 63.7 1.0 CB A:MET435 3.7 74.1 1.0 CE1 A:PHE205 3.7 52.3 1.0 CZ A:TYR589 3.9 52.8 1.0 CE1 A:PHE585 4.0 48.6 1.0 C A:THR432 4.1 54.8 1.0 CE1 A:TYR589 4.1 52.8 1.0 CA A:MET435 4.2 74.1 1.0 CA A:ILE434 4.2 68.6 1.0 C A:ILE434 4.2 68.6 1.0 CD1 A:PHE585 4.3 48.6 1.0 CB A:THR432 4.5 54.8 1.0 CA A:THR432 4.5 54.8 1.0 CB A:ILE434 4.5 68.6 1.0 CD1 A:PHE205 4.5 52.3 1.0 CZ A:PHE205 4.5 52.3 1.0 O A:GLY433 4.7 63.7 1.0 N A:ALA436 4.9 77.0 1.0 CZ A:PHE585 5.0 48.6 1.0 C A:MET435 5.0 74.1 1.0

Chlorine binding site 2 out of 4 in the Human KCC1 Structure Determined in Kcl and Lipid Nanodisc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human KCC1 Structure Determined in Kcl and Lipid Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1107 b:75.8 occ:1.00 O A:PRO429 3.4 49.4 1.0 N A:VAL135 3.5 55.6 1.0 K A:K1106 3.7 62.4 1.0 CA A:GLY134 3.7 58.1 1.0 OH A:TYR216 3.8 51.2 1.0 CE1 A:TYR216 3.8 51.2 1.0 C A:GLY134 4.0 58.1 1.0 CG1 A:VAL135 4.0 55.6 1.0 CA A:SER430 4.2 52.3 1.0 N A:GLY134 4.2 58.1 1.0 C A:PRO429 4.2 49.4 1.0 N A:ILE136 4.2 52.8 1.0 CZ A:TYR216 4.3 51.2 1.0 O A:ILE132 4.3 61.4 1.0 CE A:MET215 4.3 49.5 1.0 CD1 A:ILE136 4.5 52.8 1.0 N A:SER430 4.5 52.3 1.0 CG1 A:ILE136 4.5 52.8 1.0 CA A:VAL135 4.6 55.6 1.0 C A:PHE133 4.7 60.4 1.0 OG A:SER430 4.7 52.3 1.0 CB A:ILE136 4.7 52.8 1.0 O A:PHE133 4.8 60.4 1.0 CB A:VAL135 4.8 55.6 1.0 CD1 A:TYR216 4.9 51.2 1.0 C A:VAL135 4.9 55.6 1.0 CB A:SER430 5.0 52.3 1.0

Chlorine binding site 3 out of 4 in the Human KCC1 Structure Determined in Kcl and Lipid Nanodisc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Human KCC1 Structure Determined in Kcl and Lipid Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1106 b:65.4 occ:1.00 OH B:TYR589 2.9 52.5 1.0 N B:GLY433 3.0 64.0 1.0 N B:ILE434 3.4 68.5 1.0 CA B:GLY433 3.4 64.0 1.0 N B:MET435 3.5 73.7 1.0 CG B:MET435 3.6 73.7 1.0 CE1 B:PHE205 3.6 51.5 1.0 C B:GLY433 3.7 64.0 1.0 CB B:MET435 3.8 73.7 1.0 CE1 B:PHE585 3.9 48.5 1.0 CZ B:TYR589 4.0 52.5 1.0 C B:THR432 4.0 54.9 1.0 CD1 B:PHE585 4.1 48.5 1.0 CE1 B:TYR589 4.2 52.5 1.0 CA B:MET435 4.3 73.7 1.0 CA B:ILE434 4.3 68.5 1.0 CB B:THR432 4.4 54.9 1.0 C B:ILE434 4.4 68.5 1.0 CA B:THR432 4.4 54.9 1.0 CD1 B:PHE205 4.4 51.5 1.0 CZ B:PHE205 4.5 51.5 1.0 CB B:ILE434 4.6 68.5 1.0 O B:GLY433 4.7 64.0 1.0 CZ B:PHE585 4.8 48.5 1.0

Chlorine binding site 4 out of 4 in the Human KCC1 Structure Determined in Kcl and Lipid Nanodisc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Human KCC1 Structure Determined in Kcl and Lipid Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1108 b:75.2 occ:1.00 N B:VAL135 3.4 55.1 1.0 O B:PRO429 3.5 49.1 1.0 K B:K1107 3.7 63.3 1.0 CA B:GLY134 3.7 57.8 1.0 CE1 B:TYR216 3.8 50.7 1.0 OH B:TYR216 3.8 50.7 1.0 C B:GLY134 4.0 57.8 1.0 CG1 B:VAL135 4.0 55.1 1.0 N B:ILE136 4.2 52.1 1.0 CA B:SER430 4.2 52.5 1.0 N B:GLY134 4.2 57.8 1.0 C B:PRO429 4.2 49.1 1.0 CZ B:TYR216 4.3 50.7 1.0 CE B:MET215 4.3 48.9 1.0 O B:ILE132 4.4 61.8 1.0 CD1 B:ILE136 4.4 52.1 1.0 CG1 B:ILE136 4.4 52.1 1.0 N B:SER430 4.5 52.5 1.0 CA B:VAL135 4.5 55.1 1.0 CB B:ILE136 4.7 52.1 1.0 C B:PHE133 4.7 60.9 1.0 OG B:SER430 4.7 52.5 1.0 CB B:VAL135 4.7 55.1 1.0 O B:PHE133 4.8 60.9 1.0 C B:VAL135 4.9 55.1 1.0 CD1 B:TYR216 4.9 50.7 1.0 CB B:SER430 4.9 52.5 1.0

S.Liu, S.Chang, B.Han, L.Xu, M.Zhang, C.Zhao, W.Yang, F.Wang, J.Li, E.Delpire, S.Ye, X.C.Bai, J.Guo. Cryo-Em Structures of the Human Cation-Chloride Cotransporter KCC1. Science V. 366 505 2019.
ISSN: ESSN 1095-9203
PubMed: 31649201
DOI: 10.1126/SCIENCE.AAY3129