Chlorine in PDB 6oxb: First Bromo-Adjacent Homology (Bah) Domain of Human Polybromo-1 (PBRM1)

The structure of First Bromo-Adjacent Homology (Bah) Domain of Human Polybromo-1 (PBRM1), PDB code: 6oxb was solved by T.Petojevic, M.J.Holliday, W.J.Fairbrother, A.G.Cochran, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.40 / 1.86
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	52.304, 52.255, 120.100, 89.11, 88.24, 60.12
R / Rfree (%)	17.9 / 21.7

The binding sites of Chlorine atom in the First Bromo-Adjacent Homology (Bah) Domain of Human Polybromo-1 (PBRM1) (pdb code 6oxb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the First Bromo-Adjacent Homology (Bah) Domain of Human Polybromo-1 (PBRM1), PDB code: 6oxb:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the First Bromo-Adjacent Homology (Bah) Domain of Human Polybromo-1 (PBRM1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of First Bromo-Adjacent Homology (Bah) Domain of Human Polybromo-1 (PBRM1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1207 b:54.4 occ:1.00 OE1 A:GLN949 2.9 63.0 1.0 N B:ALA1098 3.2 25.2 1.0 NZ B:LYS1011 3.7 53.0 1.0 CA B:VAL1097 3.9 25.6 1.0 CB B:VAL1097 3.9 32.3 1.0 CB B:ALA1098 3.9 35.1 1.0 CD A:GLN949 4.0 55.0 1.0 C B:VAL1097 4.1 26.1 1.0 N A:GLN949 4.1 23.8 1.0 CA B:ALA1098 4.2 31.2 1.0 CA A:SER948 4.4 27.0 1.0 CG1 B:VAL1097 4.4 35.6 1.0 OG A:SER948 4.6 37.6 1.0 NE2 A:GLN949 4.6 51.5 1.0 CE B:LYS1011 4.7 45.6 1.0 C A:SER948 4.7 27.4 1.0 CB A:GLN949 4.9 25.9 1.0 CG B:LYS1011 4.9 26.0 1.0 O A:TYR947 4.9 27.9 1.0 CB A:SER948 5.0 30.5 1.0 CD B:LYS1011 5.0 33.5 1.0 O B:ALA1098 5.0 33.8 1.0

Chlorine binding site 2 out of 2 in the First Bromo-Adjacent Homology (Bah) Domain of Human Polybromo-1 (PBRM1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of First Bromo-Adjacent Homology (Bah) Domain of Human Polybromo-1 (PBRM1) within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl1206 b:38.2 occ:1.00 N F:LEU1007 3.2 23.0 1.0 CG F:LEU1007 3.6 17.1 1.0 CD F:ARG1010 3.6 22.6 1.0 CE2 F:PHE1070 3.7 21.3 1.0 CA F:HIS1006 3.7 21.2 1.0 CB F:HIS1006 3.8 20.9 1.0 CB F:LEU1007 3.8 18.8 1.0 CD2 F:PHE1070 3.9 20.9 1.0 O F:HOH1312 3.9 35.2 1.0 CB F:ARG1010 3.9 22.8 1.0 C F:HIS1006 3.9 23.6 1.0 NH1 F:ARG1010 4.0 23.5 1.0 CD1 F:LEU1007 4.0 31.8 1.0 CA F:LEU1007 4.1 23.5 1.0 CG F:ARG1010 4.3 22.3 1.0 NE F:ARG1010 4.6 20.9 1.0 O F:LEU1007 4.7 23.4 1.0 CZ F:PHE1070 4.7 23.5 1.0 CZ F:ARG1010 4.8 21.6 1.0 O F:HOH1346 4.8 24.1 1.0 CD2 F:LEU1007 4.9 19.6 1.0 C F:LEU1007 4.9 21.9 1.0 O F:PHE1005 5.0 25.6 1.0 CG F:PHE1070 5.0 21.9 1.0

T.Petojevic, M.J.Holliday, Y.N.Dimitrova, C.L.Noland, W.J.Fairbrother, A.G.Cochran. Polyvalent Nucleosome Recognition By Polybromo-1 Anchors Chromatin Remodeling To Be Published.