|
Atomistry » Chlorine » PDB 7avw-7b1l » 7aww | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 7avw-7b1l » 7aww » |
Chlorine in PDB 7aww: Structure of Sars-Cov-2 Main Protease Bound to ClonidineEnzymatic activity of Structure of Sars-Cov-2 Main Protease Bound to Clonidine
All present enzymatic activity of Structure of Sars-Cov-2 Main Protease Bound to Clonidine:
2.7.7.48; 3.4.19.12; 3.4.22.69; 3.6.4.12; 3.6.4.13; Protein crystallography data
The structure of Structure of Sars-Cov-2 Main Protease Bound to Clonidine, PDB code: 7aww
was solved by
S.Guenther,
P.Y.A.Reinke,
D.Oberthuer,
O.Yefanov,
L.Gelisio,
H.Ginn,
J.Lieske,
M.Domaracky,
W.Brehm,
A.Rahmani Mashour,
T.A.White,
J.Knoska,
G.Pena Esperanza,
F.Koua,
A.Tolstikova,
M.Groessler,
P.Fischer,
V.Hennicke,
H.Fleckenstein,
F.Trost,
M.Galchenkova,
Y.Gevorkov,
C.Li,
S.Awel,
L.X.Paulraj,
N.Ullah,
S.Falke,
B.Alves Franca,
M.Schwinzer,
H.Brognaro,
N.Werner,
M.Perbandt,
H.Tidow,
B.Seychell,
T.Beck,
S.Meier,
J.J.Doyle,
H.Giseler,
D.Melo,
T.J.Lane,
I.Dunkel,
A.Peck,
S.Saouane,
J.Hakanpaeae,
J.Meyer,
H.Noei,
P.Gribbon,
B.Ellinger,
M.Kuzikov,
M.Wolf,
L.Zhang,
C.Ehrt,
J.Pletzer-Zelgert,
J.Wollenhaupt,
C.Feiler,
M.Weiss,
E.C.Schulz,
P.Mehrabi,
B.Norton-Baker,
C.Schmidt,
K.Lorenzen,
R.Schubert,
H.Han,
A.Chari,
Y.Fernandez Garcia,
D.Turk,
R.Hilgenfeld,
M.Rarey,
A.Zaliani,
H.N.Chapman,
A.Pearson,
C.Betzel,
A.Meents,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Sars-Cov-2 Main Protease Bound to Clonidine
(pdb code 7aww). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Sars-Cov-2 Main Protease Bound to Clonidine, PDB code: 7aww: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 7awwGo back to Chlorine Binding Sites List in 7aww
Chlorine binding site 1 out
of 2 in the Structure of Sars-Cov-2 Main Protease Bound to Clonidine
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 7awwGo back to Chlorine Binding Sites List in 7aww
Chlorine binding site 2 out
of 2 in the Structure of Sars-Cov-2 Main Protease Bound to Clonidine
Mono view Stereo pair view
Reference:
S.Guenther,
P.Y.A.,
Reinke,
Y.,
Fernandez-Garcia,
J.,
Lieske,
T.J.,
Lane,
H.M.,
Ginn,
F.H.M.,
Koua,
C.,
Ehrt,
W.,
Ewert,
D.,
Oberthuer,
O.,
Yefanov,
S.,
Meier,
K.,
Lorenzen,
B.,
Krichel,
J.D.,
Kopicki,
L.,
Gelisio,
W.,
Brehm,
I.,
Dunkel,
B.,
Seychell,
H.,
Gieseler,
B.,
Norton-Baker,
B.,
Escudero-Perez,
M.,
Domaracky,
S.,
Saouane,
A.,
Tolstikova,
T.A.,
White,
A.,
Hanle,
M.,
Groessler,
H.,
Fleckenstein,
F.,
Trost,
M.,
Galchenkova,
Y.,
Gevorkov,
C.,
Li,
S.,
Awel,
A.Peck,
M.,
Barthelmess,
F.,
Schluenzen,
L.X.,
Paulraj,
N.,
Werner,
H.,
Andaleeb,
N.,
Ullah,
S.,
Falke,
V.,
Srinivasan,
B.,
Franca,
M.,
Schwinzer,
H.,
Brognaro,
C.,
Rogers,
D.,
Melo,
J.J.,
Doyle,
J.,
Knoska,
G.E.,
Pena Murillo,
A.,
Rahmani Mashhour,
F.,
Guicking,
V.,
Hennicke,
P.,
Fischer,
J.,
Hakanpaeae,
J.,
Meyer,
P.,
Gribbon,
B.,
Ellinger,
M.,
Kuzikov,
M.,
Wolf,
G.,
Burenkov,
D.,
Von Stetten,
G.,
Pompidor,
I.,
Bento,
S.,
Panneerselvam,
I.,
Karpics,
T.R.,
Schneider,
M.,
Garcia Alai,
S.,
Niebling,
C.,
Guenther,
C.,
Schmidt,
R.,
Schubert,
H.,
Han,
J.,
Boger,
D.,
Monteiro,
L.,
Zhang,
X.,
Sun,
J.,
Pletzer-Zelgert,
J.,
Wollenhaupt,
C.,
Feiler,
M.,
Weiss,
E.C.,
Schulz,
P.,
Mehrabi,
K.,
Karnicar,
A.,
Usenik,
J.,
Loboda,
H.,
Tidow,
A.,
Chari,
R.,
Hilgenfeld,
C.,
Uetrecht,
R.,
Cox,
A.,
Zaliani,
T.,
Beck,
M.,
Rarey,
S.,
Guenther,
D.,
Turk,
W.,
Hinrichs,
H.N.,
Chapman,
A.,
Pearson,
C.,
Betzel,
A.Meents.
Inhibition of Sars-Cov-2 Main Protease By Allosteric Drug-Binding Biorxiv 2020.
Page generated: Mon Jul 29 18:46:44 2024
DOI: 10.1101/2020.11.12.378422 |
Last articlesZn in 9JYWZn in 9IR4 Zn in 9IR3 Zn in 9GMX Zn in 9GMW Zn in 9JEJ Zn in 9ERF Zn in 9ERE Zn in 9EGV Zn in 9EGW |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |