Chlorine in PDB 7vug: Cryo-Em Structure of A Class A Orphan Gpcr in Complex with Gi

All present enzymatic activity of Cryo-Em Structure of A Class A Orphan Gpcr in Complex with Gi:
3.2.1.8;

The binding sites of Chlorine atom in the Cryo-Em Structure of A Class A Orphan Gpcr in Complex with Gi (pdb code 7vug). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of A Class A Orphan Gpcr in Complex with Gi, PDB code: 7vug:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of A Class A Orphan Gpcr in Complex with Gi


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of A Class A Orphan Gpcr in Complex with Gi within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl401 b:58.1 occ:1.00 CL1 R:7ZQ401 0.0 58.1 1.0 C3 R:7ZQ401 1.8 58.1 1.0 C2 R:7ZQ401 2.7 58.1 1.0 C4 R:7ZQ401 2.8 58.1 1.0 CB R:SER267 3.4 65.1 1.0 OG R:SER267 3.9 65.1 1.0 C1 R:7ZQ401 4.0 58.1 1.0 C5 R:7ZQ401 4.0 58.1 1.0 CG1 R:VAL263 4.2 66.6 1.0 C6 R:7ZQ401 4.6 58.1 1.0 CZ2 R:TRP170 4.7 66.0 0.5 CH2 R:TRP170 4.7 66.0 0.5 CD1 R:ILE169 4.8 65.5 1.0 CA R:SER267 4.8 65.1 1.0 CG2 R:ILE169 4.9 65.5 1.0 O R:VAL263 4.9 66.6 1.0

Y.Zhou, H.Daver, B.Trapkov, L.Wu, M.Wu, K.Harpsoe, P.R.Gentry, K.Liu, M.Larionova, J.Liu, N.Chen, H.Brauner-Osborne, D.E.Gloriam, T.Hua, Z.J.Liu. Molecular Insights Into Ligand Recognition and G Protein Coupling of the Neuromodulatory Orphan Receptor GPR139. Cell Res. 2021.
ISSN: ISSN 1001-0602
PubMed: 34916631
DOI: 10.1038/S41422-021-00591-W